Paper on HSP90

Congratulation to Mike, Nasri and Yu. Their work on the development of HSP90 inhibitors, which was conducted in collaboration with Dr Jóhannes Reynisson and his student Daniel Ayine-Tora, was accepted for publication in Bioorganic & Medicinal Chemistry Letters.

Nasri started the HSP90 work during his BScH project in 2015, which Mike has carried on during his MSc to conduct binding experiments and helped write the manuscript. Yu was the senior PhD student who looked after both Nasri and Mike in the lab and helped with protein production and purification.

You can read about their work by following this link http://doi.org/10.1016/j.bmcl.2016.11.059



2nd Green Chemistry Symposium Poster Prize

Ram Bhusal, a PhD student who is supervised by Dr Jon Sperry and co-supervised by Ivan, has shared a poster prize at the 2nd Green Chemistry Symposium that was held at the University of Auckland Conference Centre. Ram presented his work, which was conducted in the lab of Dr Sperry during the 1st year of his PhD studies, on the synthesis of value-added nitrogen-heterocycles by a sustainable approach. Well done Ram.

Ram with his poster
Ram with his poster

New Cover

Our review article “Protein-directed combinatorial chemistry: a guide to protein ligand and inhibitor discovery”, written by Mike and Ivan, has made to the cover of the July edition of the journal Molecules. You can read the article via the link here.


Moving to the City Campus

After a long wait, we are finally moving our Laboratory from our temporary home at the Old Liggins Building in Grafton to the brand new Science Centre in the City Campus. Thanks everyone for helping with the move, especially with the packing and unpacking of equipment, chemicals and biological items. Hopefully we can start working in our new lab soon!!

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Old Liggins Building

 

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Packing up

 

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Packing up

 

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Packing up

 

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Hot desk in Grafton after the move

 

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PC1 lab in Grafton after the move

 

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PC2 lab in Grafton after the move

 

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Main lab in Grafton after the move

 

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Setting up the new laboratory in City Campus

 

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Setting up the new laboratory in City Campus

 

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Setting up the new laboratory in City Campus

 

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The brand new Science Centre that we are moving into

 

 

 


Farewell lunch to Dr Leiwen Xiang

After spending a year at the University of Auckland (hosted by Professor Laurie Melton and co-hosted by us) working on milk proteins, Dr Leiwen Xiang will be returning to his native China. We wish Leiwen all the best and hope he has enjoyed his time in New Zealand.


NZIC-16

Danilo and Ivan went to the NZIC-16 meeting, which was held in Queenstown between 21st and 24th of August. Danilo presented a poster about his work on the production of LRRK2 kinase and ribosomal proteins, and Ivan gave a Talk in one of the parallel sessions on Mike’s work on the determination of binding constants by the waterLOGSY technique.

Queenstown is a beautiful place and we thank the meeting organiser for their invitations and for the successful organisation of the conference!

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Welcome new members of the group

We had a Group Lunch today to celebrate Dona handing in her BScH thesis and also welcome our two latest members – Brooke Kwai who will be doing a BScH project together with Dr Jon Sperry, and Naasson Mbenza, who will be joining as a PhD student.


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